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3-Phenylpropyl isothiocyanate

CAS No. 2627-27-2

3-Phenylpropyl isothiocyanate ( —— )

Catalog No. M28287 CAS No. 2627-27-2

3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Phenylpropyl isothiocyanate
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects.
  • Description
    3-Phenylpropyl isothiocyanate has a stronger inhibitory effect on N-nitrosomethyl-benzylamine (NMBA) tumorigenesis. 3-Phenylpropyl isothiocyanate has chemopreventive effects.(In Vivo):3-Phenylpropyl isothiocyanate (5, 1, or 0.2 μmol; gavage; A/J mice; daily for 4 consecutive days prior to administration of 10 μmol of NNK by i.p. injection) effectively inhibited NNK-induced lung tumors. In vivo, 3-Phenylpropyl isothiocyanate decreases lung tumor formation induced by benzo[a]pyrene and NNK .
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    tau;Tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2627-27-2
  • Formula Weight
    177.3
  • Molecular Formula
    C10H11NS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    S=C=NCCCC1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nozal V, et al. TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy. J Med Chem. 2022;65(2):1585-1607.
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